Unveiling Complexity: Nesidioblastosis in the Nexus of Diabetes and Chronic Kidney Disease-Reference-Cited by-同舟云学术

Unveiling Complexity: Nesidioblastosis in the Nexus of Diabetes and Chronic Kidney Disease

Published:2024-06-24 Issue: Volume:0 Page:1-2
ISSN:1998-3662
Container-title:Indian Journal of Nephrology
language:en
Short-container-title:IJN

Author:

Paladugu Niranjana Rekha¹,Vukkadala Muralinath¹,Das Anshuman¹,Sekaran Anuradha²,Merugu Chandhana³

Affiliation:

1. Department of Nephrology, Asian Institute of Gastroenterology (AIG) (Mayo clinic care network) Hospitals, Hyderabad, Telangana, India

2. Department of Pathology, Asian Institute of Gastroenterology (AIG) (Mayo clinic care network) Hospitals, Hyderabad, Telangana, India

3. Department of Endocrinology, Asian Institute of Gastroenterology (AIG) (Mayo clinic care network) Hospitals, Hyderabad, Telangana, India,

Abstract

We report a rare and intricate case of nesidioblastosis, marked by hyperinsulinemic hypoglycemia, in a patient with diabetes and chronic kidney disease (CKD). PET-CT imaging and histopathology confirmed the condition, culminating in a comprehensive treatment strategy comprising subtotal pancreatectomy and pharmacotherapy. This case marks the first documented occurrence of nesidioblastosis in a patient with CKD and diabetes. The presence of CKD further complicated the clinical picture, influencing hypoglycemic risk, drug efficacy, insulin clearance, and counter-regulatory mechanisms.

Publisher

Scientific Scholar

Reference3 articles.

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3. Adult-onset nesidioblastosis causing hypoglycemia: An important clinical entity and continuing treatment dilemma;Witteles;Arch Surg,2001