Amlodipine-Induced Gingival Enlargement – A Case Report

Abstract

One of the etiological factors for Gingival Enlargement is administration of certain drugs like calcium channel blockers, anticonvulsants, and immunosuppressant. The drug that is been commonly used for the management of portal hypertension is calcium channel blockers. Among the various drugs in calcium channel blockers, the occurrence of drug-induced gingival enlargement is high with the use of nifedipine drug whereas the occurrence of gingival enlargement due to the usage of amlodipine drug is a very rare phenomenon. Amlodipine is a third-generation drug belonging to dihydropyridine calcium channel blocker that has been used for its longer duration of action. Treatment for drug-induced gingival enlargement includes referral of patients to their physician for possible drug substitution or alteration in dosage of drug, periodontal therapy that includes oral prophylaxis followed by gingivectomy or gingivoplasty, and maintenance care. In this study, we report a case of gingival enlargement in a 44-year-old female patient taking amlodipine drug for a period of six months and nonsurgical and surgical management of amlodipine-induced gingival enlargement in the patient.