The usage of CustomFlex iris prosthesis for uveitis-induced iris defects

Abstract

Iris defects can cause glare and poor cosmesis that affects a patient’s quality of life. These defects may be caused by congenital aetiologies such as aniridia or acquired ones such as trauma and intraocular surgeries. Iris prostheses, like the CustomFlex Artificial iris by HumanOptics, were created to address these symptoms. The CustomFlex device is a stand-alone thin and foldable silicone coloured implant that could be placed in either the capsular bag or the sulcus. Because the majority of iris defects requiring prosthetic use was secondary to trauma, congenital aniridia and intraocular surgeries, our case report aims to describe usage of the CustomFlex in a patient with iris defects secondary to uveitis. Our patient presented with photophobia caused by bilateral diffuse iris atrophy with a history of herpes zoster ophthalmicus and underwent simultaneous iris prosthesis and intraocular lens implantation. The procedure improved his vision while reducing photophobia and glare. This case report shows how endocapsular implantation of the CustomFlex artificial iris, along with cataract surgery, is feasible for patients with uveitis related iris defects.