Isolation and Characterization of RNA-Directed DNA Polymerase from a B-Type RNA Tumor Virus-Reference-Cited by-同舟云学术

Isolation and Characterization of RNA-Directed DNA Polymerase from a B-Type RNA Tumor Virus

Published:1974-07 Issue:1 Volume:14 Page:40-46
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Dion Arnold S.¹,Vaidya Akhil B.¹,Fout Garland S.¹,Moore Dan H.¹

Affiliation:

1. Institute for Medical Research, Camden, New Jersey 08103

Abstract

RNA-directed DNA polymerase was isolated from milk-borne B-type murine mammary tumor virus of the RIII mouse strain. The several hundred-fold-purified enzyme sediments at 5.5 to 5.7 S with an average molecular weight of approximately 100,000. The purified enzyme is completely template dependent and responds to RNA, DNA, and synthetic templates. Stability studies indicate differential lability dependent on the exogenous template used to monitor activity.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.14.1.40-46.1974

Reference23 articles.

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