Author:
Ayakawa G Y,Williams B L,Kenny G E
Abstract
We have identified, employing two-dimensional (crossed) immunoelectrophoresis, a major heat-stable surface antigen in Actinomyces israelii with an electrophoretic mobility of 0.86 compared to bovine albumin. The surface component was protease sensitive and non-dialyzable and was found in relatively large amounts in two serotype 2 strains of A. israelii (WVU 307 and ATCC 23860). Serotype 1 strains either lacked antigen 0.86 (ATCC 12103 and CDC X522) or contained small quantities of a cross-reacting antigen which was not identical to antigen 0.86 (CDC W855). Thus, antigen 0.86 may be useful in the serotaxonomy of A. israelii. Our data also suggest the possibility that a greater degree of antigenic heterogeneity exists within the species than can be accommodated within the two currently recognized serotypes.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference31 articles.
1. Characterization of membrane and cytoplasmic antigens of Mycoplasma arginini by two-dimensional (crossed) immunoelectrophoresis;Alexander A. G.;Infect. Immun.,1977
2. Identification and quantitation of antigens and antibodies by means of quantitative immunoelectrophoresis. A survey of methods;Axelsen N. H.;J. Immunol. Methods,1972
3. Wall carbohydrate antigens of A. israelii;Bowden G. H.;Adv. Exp. Med. Biol.,1978
4. Bowden G. H. and J. M. Hardie. 1973. Commensal and pathogenic Actinomyces species in man p. 277-299. In G. Sykes and F. A. Skinner (ed.) Actinomycetales: characteristics and practical importance. Academic Press Inc. New York.
5. Antigens from Actinomyces species and their value in identification;Bowden G. H.;J. Dent. Res. 55:Al 92-A204.,1976
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献