Senescent Breast Luminal Cells Promote Carcinogenesis through Interleukin-8-Dependent Activation of Stromal Fibroblasts-Reference-Cited by-同舟云学术

Senescent Breast Luminal Cells Promote Carcinogenesis through Interleukin-8-Dependent Activation of Stromal Fibroblasts

Published:2019-01-15 Issue:2 Volume:39 Page:
ISSN:0270-7306
Container-title:Molecular and Cellular Biology
language:en
Short-container-title:Mol Cell Biol

Author:

Al-Khalaf Huda H.¹²,Ghebeh Hazem³,Inass Rabia¹,Aboussekhra Abdelilah¹

Affiliation:

1. Department of Molecular Oncology, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia

2. The National Center for Stem Cell Technology, King Abdulaziz City for Science and Technology, Riyadh, Kingdom of Saudi Arabia

3. Stem Cell & Tissue Re-Engineering Program, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia

Abstract

Aging and stress promote senescence, which has intrinsic tumor suppressor functions and extrinsic tumor promoting properties. Therefore, it is of utmost importance to delineate the effects of senescence inducers on the various types of cells that compose the different organs.

Funder

King Faisal Specialist Hospital and Research Centre

Publisher

American Society for Microbiology

Subject

Cell Biology,Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/MCB.00359-18

Reference47 articles.

1. Unveiling the Role of Senescence-Induced Cellular Plasticity

2. Aging, Cellular Senescence, and Cancer

3. The limited in vitro lifetime of human diploid cell strains