Author:
Slots J,Evans R T,Lobbins P M,Genco R J
Abstract
The agar dilution technique was used for determination of the antibiotic susceptibilities of 57 oral isolates and 2 nonoral isolates of Actinobacillus actinomycetemcomitans. Tetracycline, minocycline, and chloramphenicol inhibited more than 96% of the strains tested at a concentration of less than or equal to 2 micrograms/ml; 89% of the strains were inhibited by 2 micrograms of carbenicillin per ml. The other antimicrobial agents tested were less active. Approximately 10% of the A. actinomycetemcomitans strains were resistant to ampicillin, erythromycin, and penicillin G at concentrations of 32 to 64 micrograms/ml. These data suggest that tetracycline and minocycline may be valuable drugs in the treatment of A. actinomycetemcomitans infections.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference18 articles.
1. Treatment of anaerobic infections with lincomycin and cindamycin;Bartlett J. G.;N. Engl. J. Med.,1972
2. Actinobacillus actinomycetemcomitans endocarditis: report of a case and review of the literature;Block P. J.;Am. J. Med. Sci.,1973
3. Zur Aetiologie und Microbiologie der Aktinomykose. I. In-vitro-Versuche zur Frage der fermentativen Unterstiitzung des Actinomyces israeli durch Begleitbakterien. Zentralbl. Bakteriol. Parasitenkd;Brede H. D.;Infektionskr. Hyg. Abt. 1 Orig.,1959
4. Systemic infection due to Actinobacillus actinomycetemcomitans;Burgher L. W.;Am. J. Clin. Pathol.,1973
5. The mycelial and other micro-organisms associated with human actinomycosis;Colebrook L.;Br. J. Exp. Pathol.,1920
Cited by
79 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献