False-Positive Transcription-Mediated Amplification Assay Detection of West Nile Virus in Blood from a Patient with Viremia Caused by an Usutu Virus Infection

Author:

Gaibani Paolo1,Pierro Anna Maria1,Cavrini Francesca1,Rossini Giada1,Landini Maria Paola1,Sambri Vittorio1

Affiliation:

1. Department of Haematology and Oncology, Unit of Clinical Microbiology, Regional Reference Centre for Microbiological Emergencies (CRREM), S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy

Abstract

ABSTRACT Detection of West Nile virus (WNV) by nucleic acid amplification technology (NAAT) is used widely to screen blood and organ donations in areas where WNV is endemic. We report a false-positive result of a WNV transcription-mediated amplification assay (TMA) in a patient with viremia that was caused by Usutu virus, a mosquito-borne flavivirus.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference13 articles.

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3. Cavrini, F., P. Gaibani, G. Longo, A. M. Pierro, G. Rossini, P. Bonilauri, G. E. Gerundi, F. Di Benedetto, A. Pasetto, M. Girardis, M. Dottori, M. P. Landini, and V. Sambri. 2009. Usutu virus infection in a patient who underwent orthotropic liver transplantation, Italy, August-September 2009. Euro Surveill. 14 : pii=19448. http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=19448 .

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