Position on Mouse Chromosome 1 of a Gene that Controls Resistance to Salmonella typhimurium

Author:

Taylor Benjamin A.1,O'Brien Alison D.2

Affiliation:

1. The Jackson Laboratory, Bar Harbor, Maine 04609

2. The Department of Microbiology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20205

Abstract

Ity is a gene which regulates the magnitude of Salmonella typhimurium growth in murine tissues and, hence, the innate salmonella resistance of mice. The results of a five-point backcross clearly showed that the correct gene order on chromosome 1 is fz-Idh-1-Ity-ln-Pep-3.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference15 articles.

1. Bailey D. W. and H. P. Bunker. 1972. Mouse News Letter 47:18.

2. Genetic control of natural resistance to Leishmania donovani;Bradley D. J.;Nature (London),1974

3. Regulation of Leishmania populations within the host. II. Genetic control of acute susceptibility of mice to Leishmania donovani infection;Bradley D. J.;Clin. Exp. Immunol.,1977

4. Regulation of Leishmania populations within the host. III. Mapping of the locus controlling susceptibility to visceral leishmaniasis in the mouse;Bradley D. J.;Clin. Exp. Immunol.,1979

5. Linkage of isozyme loci in the mouse: phosphoglucomutase-2 (Pgm-2), mitochondrial NADP malate dehydrogenase (Mod-2), and dipeptidase-1 (Dip-l);Chapman V. M.;Biochem. Genet.,1971

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