Azole-Resistant Aspergillus fumigatus Clinical Isolate Screening in Azole-Containing Agar Plates (EUCAST E.Def 10.1): Low Impact of Plastic Trays Used and Poor Performance in Cryptic Species-Reference-Cited by-同舟云学术

Azole-Resistant Aspergillus fumigatus Clinical Isolate Screening in Azole-Containing Agar Plates (EUCAST E.Def 10.1): Low Impact of Plastic Trays Used and Poor Performance in Cryptic Species

Published:2021-07-16 Issue:8 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Serrano-Lobo Julia¹²^ORCID,Gómez Ana¹²^ORCID,Rodríguez-Sánchez Belén¹²^ORCID,Muñoz Patricia¹²³⁴,Escribano Pilar¹²^ORCID,Guinea Jesús¹²³^ORCID

Affiliation:

1. Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain

2. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain

3. CIBER Enfermedades Respiratorias-CIBERES (CB06/06/0058), Madrid, Spain

4. Medicine Department, Faculty of Medicine, Universidad Complutense de Madrid, Madrid, Spain

Abstract

Azole-containing agar is used in routine Aspergillus fumigatus azole resistance screening. We evaluated the impact of the type of plastic used to prepare in-house agar plates on the procedure’s performance against A. fumigatus sensu stricto and cryptic species. A. fumigatus sensu stricto ( n = 91) and cryptic species ( n = 52) were classified as susceptible or resistant (EUCAST E.Def 9.3.2; clinical breakpoints v10).

Funder

Fondo de Investigacion Sanitaria

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00482-21

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4. An expanded agar‐based screening method for azole‐resistant Aspergillus fumigatus;Mycoses;2021-11-29