Affiliation:
1. Department of Bacteriology, University of Wisconsin—Madison, Madison, Wisconsin
Abstract
SUMMARY
Carbon monoxide (CO) has long been known to have dramatic physiological effects on organisms ranging from bacteria to humans, but recently there have a number of suggestions that organisms might have specific sensors for CO. This article reviews the current evidence for a variety of proteins with demonstrated or potential CO-sensing ability. Particular emphasis is placed on the molecular description of CooA, a heme-containing CO sensor from
Rhodospirillum rubrum
, since its biological role as a CO sensor is clear and we have substantial insight into the basis of its sensing ability.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology,Infectious Diseases
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