Fatal Epstein-Barr Virus Primo Infection in a 25-Year-Old Man Treated with Azathioprine for Crohn's Disease-Reference-Cited by-同舟云学术

Fatal Epstein-Barr Virus Primo Infection in a 25-Year-Old Man Treated with Azathioprine for Crohn's Disease

Published:2009-04 Issue:4 Volume:47 Page:1252-1254
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

N'Guyen Y.¹,Andreoletti L.²,Patey M.³,Lecoq-Lafon C.⁴,Cornillet P.⁵,Léon A.⁶,Jaussaud R.¹,Fieschi C.⁷,Strady C.¹

Affiliation:

1. Service de Médicine Interne et des Maladies Infectieuses, Hôpital Robert Debré-CHU Reims, Reims, France

2. Laboratoire de Virologie Médicale et Moléculaire, EA4303/IFR53, CHU Reims, Hôpital Robert Debré, Reims, France

3. Laboratoire d'Anatomo-pathologie, Hôpital Robert Debré-CHU Reims, Avenue du Général Koenig, Reims, France

4. Laboratoire d'Hématologie, Hôpital Robert Debré-CHU Reims, Avenue du Général Koenig, Reims, France

5. Laboratoire de Cytogénétique, Hôpital Maison-Blanche-CHU Reims, Reims, France

6. Département d'Anesthésie-Réanimation, Hôpital Robert Debré-CHU Reims, Reims, France

7. Unité d'Immunopathologie, Département d'Immunologie Clinique, EA3963 Centre Hayem, Hôpital Saint Louis, 75010 Paris, France

Abstract

ABSTRACT We report a case of Epstein-Barr virus (EBV) primo infection with the development of successive infectious mononucleosis, hemophagocytic lymphohistiocytosis, and B-cell lymphoproliferative disorder in a patient treated with azathioprine for Crohn's disease. This case report suggests that specific EBV-related clinical and virological management should be considered when treating a patient with inflammatory bowel disease with azathioprine.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.02052-08

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