Small-intestinal factors promote encystation of Giardia lamblia in vitro

Author:

Gillin F D1,Reiner D S1,Boucher S E1

Affiliation:

1. Department of Pathology, University of California San Diego 92103.

Abstract

Bile salts and fatty acids stimulated differentiation of cultured Giardia lamblia trophozoites into water-resistant cysts at the slightly alkaline pH of the small intestinal lumen. Maximum encystation occurred at pH 7.8. Thus, specific small-intestinal factors may influence encystation in vivo as well as in vitro.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference17 articles.

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2. Giardia excystation can be induced in vitro in acidic solutions;Bingham A. K.;Nature (London),1979

3. Davenport H. W. 1977. Physiology of the digestive tract. Year Book Medical Publishers Chicago.

4. A new medium for the axenic cultivation of Entamoeba histolytica and other;Diamond L. S.;Entamoeba. Trans. R. Soc. Trop. Med. Hyg.,1978

5. Mammalian bile promotes growth of Giardia lamblia in axenic culture;Farthing M. J. G.;Trans. R. Soc. Trop. Med. Hyg.,1983

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