Arylamine N -Acetyltransferase Responsible for Acetylation of 2-Aminophenols in Streptomyces griseus-Reference-Cited by-同舟云学术

Arylamine N -Acetyltransferase Responsible for Acetylation of 2-Aminophenols in Streptomyces griseus

Published:2007-03 Issue:5 Volume:189 Page:2155-2159
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Suzuki Hirokazu¹,Ohnishi Yasuo¹,Horinouchi Sueharu¹

Affiliation:

1. Department of Biotechnology, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan

Abstract

ABSTRACT An arylamine N -acetyltransferase (NAT) responsible for the N acetylation of exogenous 3-amino-4-hydroxybenzoic acid in Streptomyces griseus was identified and characterized. This enzyme was distinct from other eukaryotic and bacterial NATs in that it acetylated various 2-aminophenol derivatives more effectively than it acetylated 5-aminosalicylic acid, and thus it may be involved in the metabolism of xenobiotic compounds.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.01708-06

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