pO157_Sal, a Novel Conjugative Plasmid Detected in Outbreak Isolates of Escherichia coli O157:H7

Author:

Wang Ping1,Xiong Yanwen1,Lan Ruiting2,Ye Changyun1,Wang Hua3,Ren Jun4,Jing Huaiqi1,Wang Yiting1,Zhou Zhemin5,Cui Zhigang1,Zhao Hongqing1,Chen Yuli1,Jin Dong1,Bai Xuemei1,Zhao Ailan1,Wang Yan1,Zhang Shaomin1,Sun Hui1,Li Juan1,Wang Tao6,Wang Lei5,Xu Jianguo1

Affiliation:

1. State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, China CDC, P.O. Box 5, Changping, Beijing, China

2. School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia

3. Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu Province, China

4. Anhui Provincial Center for Disease Control and Prevention, Hefei, Anhui Province, China

5. College of Life Sciences, Nankai University, Tianjin, China

6. Guizhou Medical College, Guiyang, Guizhou Province, China

Abstract

ABSTRACT In addition to the large virulence plasmid pO157, a novel 38-kb conjugative plasmid, pO157_Sal, was identified and sequenced from an Escherichia coli O157:H7 outbreak-associated Chinese isolate that shares high similarity with a plasmid in Salmonella enterica serovar Agona. The plasmid was found in 15 of 326 isolates, 12 of which were of the same pulsed-field gel electrophoresis type.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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