Diverse Commensal Escherichia coli Clones and Plasmids Disseminate Antimicrobial Resistance Genes in Domestic Animals and Children in a Semirural Community in Ecuador-Reference-Cited by-同舟云学术

Diverse Commensal Escherichia coli Clones and Plasmids Disseminate Antimicrobial Resistance Genes in Domestic Animals and Children in a Semirural Community in Ecuador

Published:2019-06-26 Issue:3 Volume:4 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Salinas Liseth¹,Cárdenas Paúl¹,Johnson Timothy J.²³,Vasco Karla¹,Graham Jay⁴,Trueba Gabriel¹^ORCID

Affiliation:

1. Microbiology Institute, Universidad San Francisco de Quito, Quito, Ecuador

2. Department of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA

3. Mid Central Research & Outreach Center, Willmar, Minnesota, USA

4. Environmental Health Sciences Division, University of California, Berkeley, California, USA

Abstract

Even though Escherichia coli strains may share nearly identical phenotypic AMR profiles and AMR genes and overlap in space and time, the diversity of clones and plasmids challenges research that aims to identify sources of AMR. Horizontal gene transfer appears to play a more significant role than clonal expansion in the spread of AMR in this community.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00316-19

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