Affiliation:
1. Laboratory of Microbiology, The Rockefeller University, New York, New York 10021
Abstract
ABSTRACT
Many glucosamine residues of the pneumococcal peptidoglycan (PG) are not acetylated, which makes the PG resistant to lysozyme. A capsular type III mutant with an inactivated
pgdA
gene (encoding the peptidoglycan
N
-acetylglucosamine deacetylase A) became hypersensitive to exogenous lysozyme and showed reduced virulence in the intraperitoneal mouse model.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Cited by
109 articles.
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