Gene Discovery in the Freshwater Fish Parasite Trypanosoma carassii : Identification of trans -Sialidase-Like and Mucin-Like Genes-Reference-Cited by-同舟云学术

Gene Discovery in the Freshwater Fish Parasite Trypanosoma carassii : Identification of trans -Sialidase-Like and Mucin-Like Genes

Published:2002-12 Issue:12 Volume:70 Page:7140-7144
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Agüero Fernán¹,Campo Vanina¹,Cremona Laura¹,Jäger Adriana¹,Di Noia Javier M.¹,Overath Peter²,Sánchez Daniel O.¹,Frasch Alberto Carlos¹

Affiliation:

1. Instituto de Investigaciones Biotecnológicas-Instituto Tecnológico de Chascomús, Universidad Nacional de General San Martín-CONICET, San Martín, 1650 Buenos Aires, Argentina

2. Max-Planck-Institut fur Biologie, Abteilung Membranbiochemie, D-72076, Tübingen, Germany

Abstract

ABSTRACT A total of 1,921 expressed sequence tags (ESTs) were obtained from bloodstream trypomastigotes of Trypanosoma carassii , a parasite of economic importance due to its high prevalence in fish farms. Analysis of the data set allowed us to identify a trans -sialidase (TS)-like gene and three ESTs coding for putative mucin-like genes. TS activity was detected in cell extracts of bloodstream trypomastigotes. We have also used the sequence information obtained to identify genes that have not been previously described in trypanosomatids. (Additional information on these ESTs can be found at http://genoma.unsam.edu.ar/projects/tca .)

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.70.12.7140-7144.2002

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