Cloning and sequence analysis of blaBIL-1, a plasmid-mediated class C beta-lactamase gene in Escherichia coli BS

Author:

Fosberry A P1,Payne D J1,Lawlor E J1,Hodgson J E1

Affiliation:

1. SmithKline Beecham Pharmaceuticals, Brockham Park, Betchworth, Surrey, United Kingdom.

Abstract

The extended-spectrum, plasmid-borne beta-lactamase gene blaBIL-1, which was discovered in Escherichia coli, has been cloned. Unusually for a plasmid-borne beta-lactamase, blaBIL-1 encodes a novel class C enzyme and appears to have originated from the chromosomal ampC gene of Citrobacter freundii.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference29 articles.

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4. Sequence of the OXA-2 b-lactamase: comparison with other penicillin-reactive enzymes;Dale J. W.;FEBS Lett.,1985

5. Devereux J. P. Haeberli and 0. Smithies. 1984. A comprehensive ANTIMICROB. AGENTS CHEMOTHER.

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