Genetic Analysis Using Vitamin B <sub>6</sub> Antagonist 4-Deoxypyridoxine Uncovers a Connection between Pyridoxal 5′-Phosphate and Coenzyme A Metabolism in Salmonella enterica-Reference-Cited by-同舟云学术

Genetic Analysis Using Vitamin B ₆ Antagonist 4-Deoxypyridoxine Uncovers a Connection between Pyridoxal 5′-Phosphate and Coenzyme A Metabolism in Salmonella enterica

Published:2022-03-15 Issue:3 Volume:204 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Vu Huong N.¹^ORCID,Downs Diana M.¹^ORCID

Affiliation:

1. Department of Microbiology, University of Georgia, Athens, Georgia, USA

Abstract

PLP is a ubiquitous cofactor required by enzymes in diverse metabolic networks. The data presented here expand our understanding of the toxic effects of dPN, a vitamin B 6 antagonist that is often used to mimic vitamin B 6 deficiency and to study PLP-dependent enzyme kinetics.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.00607-21

Reference58 articles.

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