Affiliation:
1. Department of Bacteriology, The Hebrew University, Hadassah Medical School, Jerusalem, Israel
Abstract
A mutant strain of
Pediococcus cerevisiae
was obtained which had 1,000-fold greater resistance to amethopterin than the
P. cerevisiae
/PteGlu strain. The dihydrofolate reductase level of the mutant was about 60-fold higher than that of the parent. The mutant accumulated folate, though less efficiently than its parent.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
8 articles.
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