In Vitro Resistance of Neisseria gonorrhoeae to Metronidazole-Reference-Cited by-同舟云学术

In Vitro Resistance of Neisseria gonorrhoeae to Metronidazole

Published:1974-09 Issue:3 Volume:6 Page:327-329
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Yoshikawa Thomas T.¹²³,Miyamoto Sharon¹²³,Chow Anthony W.¹²³,Guze Lucien B.¹²³

Affiliation:

1. Department of Medicine, Harbor General Hospital, Torrance, California 90509

2. Research and Medical Services, Veterans Administration Hospital (Wadsworth), Los Angeles, California 90073

3. UCLA School of Medicine, Los Angeles, California 90024

Abstract

Susceptibility of 64 clinical isolates of Neisseria gonorrhoeae to metronidazole was determined by the agar dilution technique using Mueller-Hinton and chocolate agar media. All isolates were resistant to metronidazole at 12.5 μg/ml in either medium. This lack of activity of metronidazole against N. gonorrhoeae would suggest that the ability to recover N. gonorrhoeae in patients being treated with metronidazole for concurrent Trichomonas vaginalis infections should not be hampered.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.6.3.327

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1. Phenotypic and transcriptional profiling in Entamoeba histolytica reveal costs to fitness and adaptive responses associated with metronidazole resistance;FRONT MICROBIOL;2015

2. Relative Susceptibilities of Gard ne re1 I a vaginal is (Haemophilus vaginalis), Neisseria gonorrhoeae, and Bacteroides fragilis to Metronidazole and Its Two Major Metabolites;Sexually Transmitted Diseases;1980-10

3. The Biology of the Gonococcus;CRC Critical Reviews in Microbiology;1979-01