Affiliation:
1. Department of Microbiology, The University of Sydney, Sydney, New South Wales 2006, Australia
Abstract
ABSTRACT
O antigen is part of the lipopolysaccharide present in the outer membrane of gram-negative bacteria and is highly polymorphic. In this study, we obtained sequences of the O-antigen gene clusters for the
Yersinia pseudotuberculosis
antigens IA, IIA, and IVB. We propose that the IIA gene cluster was derived from the IVB cluster, one of the very few cases in which a parent gene cluster is identified, and that the IA gene cluster could be a hybrid of the IVB and IB gene clusters. All three O antigens contain 6-deoxy
-d-
mannoheptose, and we identified six genes for the biosynthetic pathway for the precursor of this sugar, GDP-6-deoxy
-d-
mannoheptose.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference41 articles.
1. Achtman, M., K. Zurth, G. Morelli, G. Torrea, A. Guiyoule, and E. Carniel. 1999. Yersinia pestis, the cause of plague, is a recently emerged clone of Yersinia pseudotuberculosis. Proc. Natl. Acad. Sci. USA96:14043-14048.
2. Aleksic, S., G. Suchan, J. Bockemühl, and V. Aleksic. 1991. An extended antigenic scheme for Yersinia pseudotuberculosis, p. 235-238. In T. Une, T. Maruyama, and M. Tsubokura (ed.), Current investigations of the microbiology of yersiniae. Contributions to microbiology and immunology, vol. 12. Karger, Basel, Switzerland.
3. Role of the rfe gene in the biosynthesis of the Escherichia coli O7-specific lipopolysaccharide and other O-specific polysaccharides containing N-acetylglucosamine
4. Brown, P. K., L. K. Romana, and P. R. Reeves. 1992. Molecular analysis of the rfb gene cluster of Salmonella serovar Muenchen (strain M67): genetic basis of the polymorphism between groups C2 and B. Mol. Microbiol.6:1385-1394.
5. Relationships among the O-Antigen Gene Clusters of
Salmonella enterica
Groups B, D1, D2, and D3
Cited by
40 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献