The Streptococcus pyogenes Signaling Peptide SpoV Regulates Streptolysin O and Enhances Survival in Murine Blood-Reference-Cited by-同舟云学术

The Streptococcus pyogenes Signaling Peptide SpoV Regulates Streptolysin O and Enhances Survival in Murine Blood

Published:2021-05-07 Issue:11 Volume:203 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Herrera Andrea L.¹,Callegari Eduardo A.¹,Chaussee Michael S.¹

Affiliation:

1. Division of Basic Biomedical Sciences, The Sanford School of Medicine of the University of South Dakota, Vermillion, South Dakota, USA

Abstract

GAS secretes signaling peptides that can alter gene expression and impact virulence. We used peptidomics to identify a signaling peptide designated SpoV.

Funder

HHS | NIH | National Institute of General Medical Sciences

South Dakota Board of Regents

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00586-20

Reference79 articles.

1. Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus

2. Post-infectious group A streptococcal autoimmune syndromes and the heart

3. Vega LA, Malke H, McIver KS. 2016. Virulence-related transcriptional regulators of Streptococcus pyogenes. In Ferretti JJ, Stevens DL, Fischetti VA (ed), Streptococcus pyogenes: basic biology to clinical manifestations. University of Oklahoma Health Sciences Center, Oklahoma City, OK.

4. Streptolysin O and NAD-Glycohydrolase Prevent Phagolysosome Acidification and Promote Group A Streptococcus Survival in Macrophages

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Streptococcus pyogenes;Molecular Medical Microbiology;2024

2. Influenza enhances host susceptibility to non-pulmonary invasive Streptococcus pyogenes infections;Virulence;2023-10-09

3. CovS inactivation reduces CovR promoter binding at diverse virulence factor encoding genes in group A Streptococcus;PLOS Pathogens;2022-02-18

4. Signaling Peptide SpoV Is Essential for Streptococcus pyogenes Virulence, and Prophylaxis with Anti-SpoV Decreases Disease Severity;Microorganisms;2021-11-10