Characterization of rotavirus strains from newborns in New Delhi, India

Author:

Das B K1,Gentsch J R1,Cicirello H G1,Woods P A1,Gupta A1,Ramachandran M1,Kumar R1,Bhan M K1,Glass R I1

Affiliation:

1. Department of Paediatrics and Microbiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.

Abstract

Between 1986 and 1993, 72% of rotavirus strains isolated from newborns at five hospitals in New Delhi, India, had long electropherotypes, subgroup II VP6 antigens, and G and P genotypes (G9P11) identical to those of prototype strain 116E. A novel strain with a G9P6 genotype, representing 13% of the isolates, was identified. These results demonstrate that G9P11 and G9P6 rotavirus strains are common in nurseries in New Delhi.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference17 articles.

1. Protection conferred by neonatal rotavirus infection against subsequent diarrhea;Bhan M. K.;J. Infect. Dis.,1993

2. Clinical immunity after neonatal rotavirus infection: a prospective longitudinal study in young children;Bishop R. F.;N. Engl. J. Med.,1983

3. Cicirello H. B. K. Das A. Gupta M. K. Bhan J. R. Gentsch R. Kumar and R. I. Glass. High prevalence of rotavirus infection among neonates born at hospitals in Delhi India: predisposition of newborns for infection with unusual rotavirus strains. Pediatr. Infect. Dis. J. in press.

4. Das B. K. J. R. Gentsch Y. Hoshino S.-I. Ishida 0. Nakagomi M. K. Bhan R. Kumar and R. I. Glass. 1993. Characterization of 1822 NOTES

5. Both surface proteins (VP4 and VP7) of an asymptomatic neonatal rotavirus strain (1321) have high levels of sequence identity with the homologous proteins of a serotype 10 bovine rotavirus;Das M.;Virology,1993

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