Susceptibility of Haemophilus influenzae Type b to Rifampin and Sulfisoxazole

Author:

Bannatyne Robert M.1,Cheung Rose1

Affiliation:

1. Department of Bacteriology, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada

Abstract

A total of 100 and 97% of Haemophilus influenzae type b strains from major infections were susceptible, respectively, to levels of rifampin and sulfisoxazole attainable in saliva. It is theoretically feasible to eliminate Haemophilus influenzae from the nasopharynx with these drugs.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference10 articles.

1. Rifampin levels in serum and saliva and effect on the meningococcal carrier state;Devine L. F.;J. Am. Med. Assoc.,1970

2. Devine L. F. R. C. Knowles W. E. Pierce R. 0. Peckinpaugh C. R. Hagerman and R. I. Lytle. 1969. Proposed model for screening antimicrobial agents for potential use in eliminating meningococci from the nasopharynx of healthy carriers p. 307-314. Antimicrob. Agents Chemother. 1968.

3. Hemophilus influenzae type B susceptibility to 17 antibiotics;Emerson B. B.;J. Pediatr.,1975

4. An outbreak of Haemophilus influenzae type b meningitis in an enclosed hospital population;Glode M. D.;J. Pediatr.,1976

5. H. influenzae meningitis;Kline H. A.;Am. J. Dis. Child.,1962

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