Detection of Rocky Mountain spotted fever antibodies by a latex agglutination test

Author:

Hechemy K E,Anacker R L,Philip R N,Kleeman K T,MacCormack J N,Sasowski S J,Michaelson E E

Abstract

A latex test for immunodiagnosis of Rocky Mountain spotted fever, using erythrocyte-sensitizing substance from Rickettsia rickettsii adsorbed to latex particles, has been developed. The test was evaluated with a total of 123 single and 118 paired human sera submitted for Rocky Mount spotted fever testing. This test is simple, sensitive, and specific. Its efficiency, relative to the reference microimmunofluorescence test, was 95.1% for single sera and approached 100% for paired sera.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference19 articles.

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3. Rocky Mountain spotted fever-United States;Center for Disease Control.;Morbid. Mortal. Weekly Rep.,1978

4. A microagglutination technique for detection and measurement of rickettsial antibodies;Fiset P. I.;Acta Virol. Engl. Ed.,1969

5. Fleiss J. L 1973. Statistical methods for rates and proportions p. 140-154. John Wiley & Sons Inc. New York.

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