Affiliation:
1. Shionogi Research Laboratory, Shionogi and Co., Ltd., Fukushima-ku, Osaka, 553 Japan
Abstract
Ribosomes from an erythromycin-producing strain,
Streptomyces erythreus
, lacked affinity for erythromycin and were also resistant to other macrolide antibiotics (leucomycin, spiramycin, and tylosin) and to lincomycin, whereas
Streptomyces griseus
B
3
ribosomes were susceptible to all of these antibiotics.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference30 articles.
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4. The specificity of lincomycin binding to ribosomes;Chang F. N.;Biochemistry,1967
5. Corcoran J. W. 1971. Erythromycin and the bacterial ribosome: a study of the mechanism of sensitivity and resistance to macrolide antibiotics and lincomycin in Bacillus subtilis 168 p. 17 7-200. In S. Mitsuhashi (ed.) Drug action and drug resistance in bacteria. 1. Macrolide antibiotics and lincomycin. University of Tokyo Press Tokyo.
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