Leishmanicidal Activity of Isoselenocyanate Derivatives

Author:

Fernández-Rubio Celia123,Larrea Esther13,Peña Guerrero José12,Sesma Herrero Eduardo12,Gamboa Iñigo12,Berrio Carlos12,Plano Daniel14,Amin Shantu5,Sharma Arun K.5,Nguewa Paul A.123

Affiliation:

1. Universidad de Navarra, Instituto de Salud Tropical (ISTUN), Pamplona, Spain

2. Universidad de Navarra, Department of Microbiology and Parasitology, Pamplona, Spain

3. IdiSNA, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain

4. Universidad de Navarra, Department of Organic and Pharmaceutical Chemistry, Pamplona, Spain

5. Department of Pharmacology, Penn State Cancer Institute, CH72, Penn State College of Medicine, Hershey, Pennsylvania, USA

Abstract

Conventional chemotherapy against leishmaniasis includes agents exhibiting considerable toxicity. In addition, reports of drug resistance are not uncommon.

Funder

Obra Social La Caixa and Fundación Caja Navarra

Gobierno de Navarra Salud

Fundación Roviralta

Ubesol

Government of Navarre I+D

Ministerio de Educación, Cultura y Deporte

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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