In Vitro Activities of Telavancin and Six Comparator Agents against Anaerobic Bacterial Isolates

Author:

Finegold Sydney M.123,Bolanos Mauricio4,Sumannen Paula H.4,Molitoris Denise R.4

Affiliation:

1. Medical

2. Medicine

3. Microbiology, Immunology and Molecular Genetics, UCLA School of Medicine, Los Angeles, California

4. Research Services, Veterans Administration Greater Los Angeles Healthcare System, and Departments of

Abstract

ABSTRACT The antimicrobial activities of telavancin and six comparators were evaluated against 460 isolates of anaerobic bacteria. Telavancin demonstrated excellent activity against gram-positive anaerobes (MIC 90 , 2 μg/ml) and was the most potent agent tested against Clostridium difficile (MIC 90 , 0.25 μg/ml). As expected, gram-negative isolates were not inhibited by telavancin.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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