Thrombin-Derived C-Terminal Peptide Reduces Candida -Induced Inflammation and Infection In Vitro and In Vivo

Author:

Dahlman Anna1,Puthia Manoj2,Petrlova Jitka2,Schmidtchen Artur234,Petruk Ganna12ORCID

Affiliation:

1. Xinnate AB, Medicon Village, Lund, Sweden

2. Division of Dermatology and Venereology, Department of Clinical Sciences, Faculty of Medicine, Lund University, Lund, Sweden

3. Copenhagen Wound Healing Center, Bispebjerg Hospital, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark

4. Dermatology, Skåne University Hospital, Lund, Sweden

Abstract

Infections due to the opportunistic fungus Candida have been on the rise in the last decades, especially in immunocompromised individuals and hospital settings. Unfortunately, the treatments available today are limited.

Funder

Swedish Research Council

Kungliga Fysiografiska Sällskapet i Lund

Stiftelsen Lars Hiertas Minne

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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