Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages-Reference-Cited by-同舟云学术

Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages

Published:2022-12-20 Issue:12 Volume:66 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Sake Svenja M.¹,Kosch Christina²³,Blockus Sebastian¹,Haid Sibylle¹,Gunesch Antonia P.¹,Zhang Xiaoyu¹,Friesland Martina¹,Trummer Sofie B.¹,Grethe Christina¹,Kühnel Anne¹,Rückert Jessica⁴⁵,Duprex W. Paul⁶,Huang Jiabin⁷,Rameix-Welti Marie-Anne⁸^ORCID,Empting Martin²³,Fischer Nicole⁷,Hirsch Anna K. H.²³⁹¹⁰,Schulz Thomas F.⁴⁵¹⁰^ORCID,Pietschmann Thomas¹⁵⁹¹⁰^ORCID

Affiliation:

1. Institute for Experimental Virology, Twincore-Centre for Experimental and Clinical Infection Research, Hanover, Germany

2. Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany

3. Department of Pharmacy, Saarland University, Saarbrücken, Germany

4. Institute of Virology, Hanover Medical School, Hanover, Germany

5. German Centre for Infection Research, Hanover-Braunschweig Site, Hanover, Germany

6. Centre for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

7. Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

8. Université Paris-Saclay, Université de Versailles St. Quentin, UMR 1173 (2I), INSERM, Assistance Publique des Hôpitaux de Paris, Hôpital Ambroise Paré, Laboratoire de Microbiologie, Versailles, France

9. Helmholtz International Lab for Anti-Infectives, Helmholtz Center for Infection Research, Braunschweig, Germany

10. Cluster of Excellence RESIST (EXC 2155), Hanover Medical School, Hanover, Germany

Abstract

Human respiratory syncytial virus (hRSV) infection is a leading cause of severe respiratory tract infections. Effective, directly acting antivirals against hRSV are not available.

Funder

Deutsche Forschungsgemeinschaft

SARS-CoV-2 Immediate Response Initiative Funded by the State of Lower Saxony

INDIRA Project

Helmholtz International Lab for Anti-Infectives

German Centre for Infection Research

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.01032-22