Affiliation:
1. Institute of Molecular Genetics, University of California, San Diego, La Jolla 92093.
Abstract
A variant clone of vesicular stomatitis virus recovered from a high-passage, evolving virus population replicated rapidly and produced remarkably high yields of virus, but these variants never dominated during further passages. We show that this clone is highly competitive, but it can overwhelm its progenitor population only when seeded above threshold level during dilute passages.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Cited by
172 articles.
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