Local Adaptation of Legionella pneumophila within a Hospital Hot Water System Increases Tolerance to Copper

Author:

Bédard Emilie12ORCID,Trigui Hana1,Liang Jeffrey2,Doberva Margot1,Paranjape Kiran2,Lalancette Cindy3,Allegra Séverine4,Faucher Sebastien P.2ORCID,Prévost Michèle1

Affiliation:

1. Department of Civil Engineering, Polytechnique Montréal, Montréal, Quebec, Canada

2. Department of Natural Resource Sciences, Faculty of Agricultural and Environmental Sciences, McGill University, Sainte-Anne-de-Bellevue, Quebec, Canada

3. Laboratoire de Santé Publique du Québec, Sainte-Anne-de-Bellevue, Quebec, Canada

4. University of Lyon, UJM-Saint-Etienne, UMR 5600 CNRS, EVS-ISTHME, Saint-Etienne, France

Abstract

Legionella pneumophila is a pathogen indigenous to natural and large building water systems in the bulk and the biofilm phases. The immediate environment within a system can impact the tolerance of L. pneumophila to environmental stressors, including copper.

Funder

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference82 articles.

1. Legionella and Legionnaires' Disease: 25 Years of Investigation

2. Surveillance for Waterborne Disease Outbreaks Associated with Drinking Water — United States, 2013–2014

3. Vital Signs: Deficiencies in Environmental Control Identified in Outbreaks of Legionnaires’ Disease — North America, 2000–2014

4. European Centre for Disease Prevention and Control. 2017. Legionnaires' disease. In ECDC annual epidemiological report for 2015. European Centre for Disease Prevention and Control Stockholm Sweden. https://www.ecdc.europa.eu/sites/default/files/documents/AER_for_2015-legionnaires-disease_0.pdf.

5. Centers for Disease Control and Prevention. 2017. Active bacterial core surveillance (ABCs) report emerging infections program network: legionellosis 2015. CDC Atlanta GA.

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