The Role of the BCL-2 Family of Proteins in HIV-1 Pathogenesis and Persistence-Reference-Cited by-同舟云学术

The Role of the BCL-2 Family of Proteins in HIV-1 Pathogenesis and Persistence

Published:2019-12-18 Issue:1 Volume:33 Page:
ISSN:0893-8512
Container-title:Clinical Microbiology Reviews
language:en
Short-container-title:Clin Microbiol Rev

Author:

Chandrasekar Aswath P.¹,Cummins Nathan W.¹^ORCID,Badley Andrew D.¹²

Affiliation:

1. Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA

2. Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, USA

Abstract

Advances in HIV-1 therapy have transformed the once fatal infection into a manageable, chronic condition, yet the search for a widely applicable approach to cure remains elusive. The ineffectiveness of antiretroviral therapy (ART) in reducing the size of the HIV-1 latent reservoir has prompted investigation into the mechanisms of HIV-1 latency and immune escape.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,General Immunology and Microbiology,Epidemiology

Link

https://journals.asm.org/doi/pdf/10.1128/CMR.00107-19

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