Affiliation:
1. Division of Infectious Disease
2. Division of Microbiology, Long Island Jewish Medical Center, Albert Einstein College of Medicine, New Hyde Park, New York 11042
Abstract
ABSTRACT
We investigated the in vitro susceptibilities of 23
Propionibacterium acnes
ophthalmic isolates to ertapenem, meropenem, and cefepime by utilizing the Etest. The MICs ranged from 0.094 μg/ml to 0.75 μg/ml, 0.094 μg/ml to 1.5 μg/ml, and 1 μg/ml to 12 μg/ml for ertapenem, meropenem, and cefepime, respectively. Based on our excellent in vitro carbapenem susceptibility results, in vivo studies using ertapenem and meropenem in a rabbit model of
P. acnes
endophthalmitis are warranted.
Publisher
American Society for Microbiology
Reference11 articles.
1. Aldave, A. J., J. D. Stein, V. A. Deramo, G. K. Shah, D. H. Fischer, and J. I. Maguire. 1999. Treatment strategies for postoperative Propionibacterium acnes endophthalmitis. Ophthalmology106:2395-2401.
2. Brady, S. E., E. J. Cohen, and D. H. Fischer. 1988. Diagnosis and treatment of chronic post-operative bacterial endophthalmitis. Ophthalmol. Surg.19:580-584.
3. Evaluation of the E test for susceptibility testing of anaerobic bacteria
4. Clark, W. L., P. K. Kaiser, H. W. Flynn, Jr., A. Belfort, D. Miller, and D. M. Meisler. 1999. Treatment strategies and visual acuity outcomes in chronic post-operative Propionibacterium acnes endophthalmitis. Ophthalmology106:1665-1670.
5. Clinical and Laboratory Standards Institute. 2005. Performance standards for antimicrobial susceptibility testing 15th informational supplement M100-S15. Clinical and Laboratory Standards Institute Wayne Pa.
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