NanJ Is the Major Sialidase for Clostridium perfringens Type F Food Poisoning Strain 01E809

Abstract

Clostridium perfringens type F strains cause food poisoning (FP) when they sporulate and produce C. perfringens enterotoxin (CPE) in the intestines. Most type F FP strains carry a chromosomal cpe gene (c- cpe strains). C. perfringens produces up to three different sialidases, named NanH, NanI, and NanJ, but some c- cpe FP strains carry only nanJ and nanH genes.