Affiliation:
1. Department of Microbiology, The Pennsylvania State University, University Park, Pennsylvania
Abstract
Raycroft, Ruth
E. (The Pennsylvania State University, University Park),
and L. N. Zimmerman
. New mode of genetic transfer in
Streptococcus faecalis
var.
liquefaciens
. J. Bacteriol.
87:
799–801. 1964.—When chloramphenicol-resistant mutants are grown in mixed culture with the sensitive wild type of
Streptococcus faecalis
var.
liquefaciens
31, a transfer of chloramphenicol resistance occurs. (The marker is stable through at least five transfers.) The transfer mechanism is not inhibited by deoxyribonuclease, nor is it phage-mediated; genetic transfer is apparently dependent upon cell contact. Although kinetic studies have yet to be completed, preliminary data indicate a high efficiency (2.2 per donor cell in some experiments) of transmission. Two levels of drug resistance, 7 and 50 μg, were transferred; in each case, recipient cells expressed the donor's degree of resistance.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
19 articles.
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