Affiliation:
1. Max-Planck-Institut für Biologie, Tübingen, Federal Republic of Germany.
Abstract
Assembly of the long tail fibers of the Escherichia coli bacteriophage T4 requires the catalytic action of two auxiliary proteins. It was found that a gene of the entirely unrelated phage lambda codes for a protein which can substitute for one of these T4 polypeptides, protein 38. The lambda gene was designated tfa (tail fiber assembly). Protein 38 consists of 183 residues, and the Tfa protein consists of 194 residues; the two polypeptides are about 40% homologous. Although the tfa gene is dispensable for the growth of phage lambda, these results indicate that it may have a function in lambda morphogenesis.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference26 articles.
1. 13eginning a genetic analysis of conjugational transfer determined by the F factor in Escherichia coli by isolation and characterization of transfer-deficient mutants;Achtinan M.;J. Bacteriol.,1971
2. Structure of bacteriophage T4 genes 37 and 38;Beckendorf S. K.;J. Mol. Biol.,1973
3. Court D. and A. B. Oppenheimn 1983. Phage lambda's accessory genes p. 251-277. In R. W. Hendrix J. W. Roberts F. W. Stahl and R. A. Weisberg (ed.); Lambda II. Cold Spring Harbor Laboratory Cold Spring Harbor N.Y.
4. Daniels D. L. 3. L. Schroeder W. Szybalski F. Sanger A. R. Coulson G. F. Hong D. F. Hili G. B. Petersen and F. R. Blattner. 1983. Complete annotated lambda sequence p. 519-676. In R. W. Hendrix J. W. Roberts F. W. Stahl and R. A. Weisberg (ed.) Lambda II. Cold Spring Harbor Laboratory Cold Spring Harbor N.Y.
5. Establishing homologies in protein se 4uences;Dayhoff M. O.;Methods Enzymol.,1983
Cited by
16 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献