Guinea pig model for Staphylococcus aureus native valve endocarditis-Reference-Cited by-同舟云学术

Guinea pig model for Staphylococcus aureus native valve endocarditis

Published:1997-08 Issue:8 Volume:41 Page:1815-1817
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Maurin M¹,Lepidi H¹,La Scola B¹,Feuerstein M¹,Andre M¹,Pellissier J F¹,Raoult D¹

Affiliation:

1. Unité des Rickettsies, CNRS EP J0054, Faculté de Médecine, CHU Timone, Marseille, France.

Abstract

We present a new experimental model of Staphylococcus aureus infective endocarditis in guinea pigs. Permanent aortic valve damage was produced by electrocoagulation after catheterization of the right carotid artery, which allowed avoidance of the intracardiac catheter to produce cardiac vegetations. Our model closely mimics pathological mechanisms of native valve endocarditis.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.41.8.1815

Reference16 articles.

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4. Experimental infective endocarditis;Freedman L. R.;Prog. Cardiovasc. Dis.,1979

5. Experimental endocarditis. I. Staphylococcal endocarditis in rabbits resulting from placement of a polyethylene catheter in the right side of the heart;Garrison P. K.;Yale J. Biol. Med.,1970

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