A novel malaria protein, Pfs28, and Pfs25 are genetically linked and synergistic as falciparum malaria transmission-blocking vaccines-Reference-Cited by-同舟云学术

A novel malaria protein, Pfs28, and Pfs25 are genetically linked and synergistic as falciparum malaria transmission-blocking vaccines

Published:1997-03 Issue:3 Volume:65 Page:1109-1113
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Duffy P E¹,Kaslow D C¹

Affiliation:

1. Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892-0425, USA.

Abstract

Antibodies to Pfs28 block Plasmodium falciparum transmission and when combined with antibodies to Pfs25 provide synergy in blocking transmission. Pfs28 and Pfs25 are immunogenic, have limited antigenic diversity, and are structurally similar and genetically linked on chromosome 10. Pfs28 may prove a useful addition to Pfs25 in an effective transmission-blocking vaccine.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.65.3.1109-1113.1997

Reference14 articles.

1. Recombinant Pfs25 protein of Plasmodium falciparum elicits malaria transmission-blocking immunity in experimental animals;Barr P. J.;J. Exp. Med.,1991

2. Pgs28 belongs to a family of epidermal growth factor-like antigens that are targets of malaria transmission-blocking antibodies;Duffy P. E.;J. Exp. Med.,1993

3. Antigenic diversity and the transmission dynamics of Plasmodium falciparum;Gupta S.;Science,1994

4. Transmission-blocking immunity against malaria and other vector-borne diseases;Kaslow D. C.;Curr. Opin. Immunol.,1993

5. Production, purification and immunogenicity of malaria transmission-blocking vaccine candidate: TBV25H expressed in yeast and purified using nickel-NTA agarose;Kaslow D. C.;Bio/Technology,1994

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