Genomic and Phylogenetic Analysis of Hepatitis C Virus Isolates from Argentine Patients: a Six-Year Retrospective Study-Reference-Cited by-同舟云学术

Genomic and Phylogenetic Analysis of Hepatitis C Virus Isolates from Argentine Patients: a Six-Year Retrospective Study

Published:2000-12 Issue:12 Volume:38 Page:4560-4568
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Quarleri J. F.¹,Robertson B. H.²,Mathet V. L.¹,Feld M.¹,Espı́nola L.¹,Requeijo M. P.³,Mandó O.³,Carballal G.³,Oubiña J. R.¹

Affiliation:

1. Laboratorio de Hepatitis Virales, Departamento Microbiologı́a, Facultad de Medicina, Universidad de Buenos Aires,1 and

2. Centers for Disease Control and Prevention, Atlanta, Georgia2

3. CEMIC,3 Buenos Aires, Argentina, and

Abstract

ABSTRACT Typing of hepatitis C virus (HCV) isolates from Argentine patients was performed by using different methodologies in a population of 243 patients. HCV subtype was assigned based upon restriction fragment length polymorphism (RFLP). HCV RNA genomes obtained from serum samples were classified as belonging to clade 1 (53.5%), 2 (23.0%), or 3 (8.6%); 14.8% of samples showed HCV mixed infections, more frequently implying different subtypes within the same clade. In addition to RFLP typing, phylogenetic relatedness among sequences from both 5′ untranslated region ( n = 50) and nonstructural 5B coding region ( n = 15) was established.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.38.12.4560-4568.2000

Reference51 articles.

1. Perspectives for a hepatitis C virus vaccine;Abrignani S.;Clin. Diagn. Virol.,1998

2. Genotyping of Canadian hepatitis C virus isolates by PCR

3. Typing of hepatitis C virus by a new method based on restriction fragment length polymorphism;Buoro S.;Intervirology,1999

4. Partial nucleotide sequencing of six subtype 2c hepatitis C viruses detected in Italy

5. Comparison of several PCR procedures for detection of serum HCV-RNA using different regions of the HCV genome;Castillo I.;J. Virol. Methods,1992

Cited by 25 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Análisis del virus de la hepatitis C en pacientes en hemodiálisis;Infectio;2016-07

2. Phylogenetic Analysis and Epidemic History of Hepatitis C Virus Genotype 2 in Tunisia, North Africa;PLOS ONE;2016-04-21

3. HIV, HBV, and HCV molecular epidemiology among trans (transvestites, transsexuals, and transgender) sex workers in Argentina;Journal of Medical Virology;2013-10-12

4. Molecular epidemiology and putative origin of hepatitis C virus in random volunteers from Argentina;World Journal of Gastroenterology;2013

5. A clustering phenomenon among HCV-1a strains among patients coinfected with HIV from Buenos Aires, Argentina;Journal of Medical Virology;2012-02-15