Extended-Spectrum β-Lactamase Enzymes in Clinical Isolates of Enterobacter Species from Lagos, Nigeria

Author:

Aibinu I. E.1,Ohaegbulam V. C.1,Adenipekun E. A.1,Ogunsola F. T.1,Odugbemi T. O.1,Mee B. J.2

Affiliation:

1. Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, P.M.B 12003, Lagos, Nigeria

2. Department of Microbiology, School of Biomedical and Chemical Sciences, The University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands 6009, Western Australia, Australia

Abstract

ABSTRACT Over a 9-month period, 8 of 40 nonduplicate isolates of Enterobacter spp. producing extended-spectrum β-lactamase (ESBL) were detected for the first time from two hospitals in Lagos, Nigeria. Microbiologic and molecular analysis confirmed the presence of ESBL. Only four isolates transferred ESBL resistance as determined by the conjugation test, and pulsed-field gel electrophoresis showed genetically unrelated isolates.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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