Affiliation:
1. Department of Food Technology and Biochemical Engineering, Jadavpur University, Calcutta-32, India
Abstract
To select a suitable synthetic medium for kanamycin production, we tested a number of carbon and nitrogen compounds for their effect on growth of
Streptomyces kanamyceticus
ATCC 12853 as well on kanamycin production. Galactose was found to be the most suitable carbon source, though dextrin, soluble starch, and potato starch gave moderate yields. Sodium nitrate and glycine were adequate nitrogen sources for kanamycin production. There was, however, no direct relation between the growth of the organism and antibiotic formation. The pH of the medium might be an important factor for kanamycin formation, as media giving high kanamycin yields showed an alkaline pH without exception.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
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