Efficacies of Amphotericin B (AMB) Lipid Complex, AMB Colloidal Dispersion, Liposomal AMB, and Conventional AMB in Treatment of Murine Coccidioidomycosis-Reference-Cited by-同舟云学术

Efficacies of Amphotericin B (AMB) Lipid Complex, AMB Colloidal Dispersion, Liposomal AMB, and Conventional AMB in Treatment of Murine Coccidioidomycosis

Published:2004-06 Issue:6 Volume:48 Page:2140-2143
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

González Gloria M.¹²,Tijerina Rolando²,Najvar Laura K.¹,Bocanegra Rosie¹,Rinaldi Michael G.³,Graybill John R.¹

Affiliation:

1. Department of Medicine, Division of Infectious Diseases

2. Departamento de Microbiología, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo Léon, Mexico

3. Fungus Testing Laboratory, Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229-3900

Abstract

ABSTRACT The therapeutic efficacy of three lipid formulations of amphotericin B was compared with that of conventional amphotericin B in treatment of murine coccidioidomycosis. All treatments prolonged survival compared with the no-treatment group ( P < 0.0001). Although conventional amphotericin B was more active than lipid formulations on reducing quantitative fungal load on a milligram-per-kilogram basis ( P < 0.003 to 0.0002), the lipid preparations could be administered at higher doses, sterilizing liver and spleen tissues. The efficacies of the lipid preparations were similar in this murine model of coccidioidomycosis.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.48.6.2140-2143.2004

Reference17 articles.

1. Albert, M. M., K. Adams, M. J. Luther, S. H. Sun, and J. R. Graybill. 1994. Efficacy of AmBisome in murine coccidioidomycosis. J. Med. Vet. Mycol.32:467-471.

2. Comparative efficacy of amphotericin B colloidal dispersion and amphotericin B deoxycholate suspension in treatment of murine coccidioidomycosis

3. Clemons, K. V., and D. A. Stevens. 1992. Efficacies of amphotericin B lipid complex (ABLC) and conventional amphotericin B against murine coccidioidomycosis. J. Antimicrob. Chemother.30:353-363.

4. Clemons, K. V., and D. A. Stevens. 1993. Comparison of a liposomal amphotericin B formulation (ambisome) and deoxycholate amphotericin B (fungizone) for the treatment of murine paracoccidioidomycosis. J. Med. Vet. Mycol.31:387-394.

5. Comparison of Fungizone, Amphotec, AmBisome, and Abelcet for Treatment of Systemic Murine Cryptococcosis

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A microbial risk assessor's guide to Valley Fever (Coccidioides spp.): Case study and review of risk factors;Science of The Total Environment;2024-03

2. Coccidioidomycosis: A Contemporary Review;Infectious Diseases and Therapy;2022-03-01

3. Nanomaterial-Based Antifungal Therapies to Combat Fungal Diseases Aspergillosis, Coccidioidomycosis, Mucormycosis, and Candidiasis;Pathogens;2021-10-12

4. The Rise of Coccidioides: Forces Against the Dust Devil Unleashed;Frontiers in Immunology;2019-09-11

5. Current Concepts and Future Directions in the Pharmacology and Treatment of Coccidioidomycosis;Medical Mycology;2019-01-25