Factors Associated with Breakthrough Fungemia Caused by Candida , Trichosporon , or Fusarium Species in Patients with Hematological Disorders

Author:

Kimura Muneyoshi1ORCID,Asano-Mori Yuki2,Sakoh Takashi1,Abe Masahiro3,Ueno Keigo3,Hoshino Yasutaka3,Nakamura Shigeki34,Umeyama Takashi3,Yamagoe Satoshi3,Miyazaki Yoshitsugu3ORCID,Baba Masaru1,Okada Chikako1,Ogura Sho1,Mitsuki Takashi5,Yamaguchi Kyosuke2,Yuasa Mitsuhiro2,Kaji Daisuke2,Kageyama Kosei2,Nishida Aya5,Taya Yuki2,Ishiwata Kazuya5,Takagi Shinsuke2,Yamamoto Hisashi2,Yamamoto Go2,Uchida Naoyuki26,Wake Atsushi56,Taniguchi Shuichi26,Araoka Hideki16ORCID

Affiliation:

1. Department of Infectious Diseases, Toranomon Hospital, Tokyo, Japan

2. Department of Hematology, Toranomon Hospital, Tokyo, Japan

3. Department of Fungal Infection, National Institute of Infectious Diseases, Tokyo, Japan

4. Department of Microbiology, Tokyo Medical University, Tokyo, Japan

5. Department of Hematology, Toranomon Hospital Kajigaya, Kanagawa, Japan

6. Okinaka Memorial Institute for Medical Research, Tokyo, Japan

Abstract

Limited data are available on breakthrough fungemia, defined as fungemia that develops on administration of antifungal agents, in patients with hematological disorders. We reviewed the medical and microbiological records of adult patients with hematological diseases who had breakthrough fungemia between January 2008 and July 2019 at Toranomon Hospital and Toranomon Hospital Kajigaya in Japan.

Funder

Japan Agency for Medical Research and Development

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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