Coproduction of Tet(X7) Conferring High-Level Tigecycline Resistance, Fosfomycin FosA4, and Colistin Mcr-1.1 in Escherichia coli Strains from Chickens in Egypt-Reference-Cited by-同舟云学术

Coproduction of Tet(X7) Conferring High-Level Tigecycline Resistance, Fosfomycin FosA4, and Colistin Mcr-1.1 in Escherichia coli Strains from Chickens in Egypt

Published:2021-05-18 Issue:6 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Soliman Ahmed M.¹²^ORCID,Ramadan Hazem³⁴^ORCID,Zarad Hoda⁵,Sugawara Yo⁶,Yu Liansheng⁶,Sugai Motoyuki⁶^ORCID,Shimamoto Toshi⁷,Hiott Lari M.³,Frye Jonathan G.³,Jackson Charlene R.³,Shimamoto Tadashi⁷^ORCID

Affiliation:

1. Laboratory of Food Microbiology and Hygiene, Graduate School of Biosphere Science, Hiroshima University, Higashihiroshima, Japan

2. Department of Microbiology and Immunology, Faculty of Pharmacy, Kafrelsheikh University, Kafr El-Sheikh, Egypt

3. Bacterial Epidemiology and Antimicrobial Resistance Research Unit, U.S. National Poultry Research Center, USDA-ARS, Athens, Georgia, USA

4. Hygiene and Zoonoses Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt

5. Sidi Ghazy Public Hospital, Sidi Ghazy City, Kafr El-Sheikh, Egypt

6. Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Higashimurayama, Japan

7. Laboratory of Food Microbiology and Hygiene, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashihiroshima, Japan

Abstract

The plasmid-mediated tet (X7) conferring high-level tigecycline resistance was identified in five mcr-1.1 -positive Escherichia coli strains (ST10 [ n = 3] and ST155 [ n = 2]) isolated from chickens in Egypt. Two fosfomycin-resistant fosA4 -carrying IncFII plasmids (⁓79 kb in size) were detected.

Funder

Ministry of Health, Labour and Welfare

U.S. Department of Agriculture

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02084-20

Reference26 articles.

1. Emergence of plasmid-mediated high-level tigecycline resistance genes in animals and humans

2. Plasmid-encoded tet(X) genes that confer high-level tigecycline resistance in Escherichia coli