Performance of Bayesian Area Under the Concentration-Time Curve-Based Pharmacokinetic Dosing Based on a One-Compartment Model and Trough-Only Monitoring for Vancomycin-Reference-Cited by-同舟云学术

Performance of Bayesian Area Under the Concentration-Time Curve-Based Pharmacokinetic Dosing Based on a One-Compartment Model and Trough-Only Monitoring for Vancomycin

Published:2023-06-15 Issue:6 Volume:67 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Salehpour Niloufar¹,Riley Lacey D.¹²,Gonzales Marcos J.¹,Kobic Emir¹²,Nix David E.¹³^ORCID

Affiliation:

1. Department of Pharmacy Practice and Science, University of Arizona College of Pharmacy, Tucson, Arizona, USA

2. Banner University Medical Center—Phoenix, Phoenix, Arizona, USA

3. Banner University Medical Center—Tucson, Tucson, Arizona, USA

Abstract

A novel Bayesian method was developed to interpret serum vancomycin concentrations (SVCs) following the administration of one or more vancomycin doses with potential varying doses and intervals based on superposition principles. The method was evaluated using retrospective data from 442 subjects from three hospitals.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.00172-23

Reference18 articles.

1. Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists

2. Keil E Wrenn RH Deri CR Slaton CN Shroba J Parish A Erkanli A Spivey J. 1 December 2022. Comparison of open-access trough-only online calculators versus trapezoidal method for calculation of vancomycin area under the curve (AUC). Ann Pharmacother.

3. Bayesian Individualization of Pharmacokinetics: Simple Implementation and Comparison with Non-Bayesian Methods

4. D’Argenio DZ, Schumitzky A, Wang X. 2009. ADAPT 5 user’s guide: pharmacokinetic/pharmacodynamic systems analysis software. Biomedical Simulations Resource, Los Angeles, CA.

5. Vancomycin population pharmacokinetics for adult patients with sepsis or septic shock: are current dosing regimens sufficient?