bcr/abl and src but not myc and ras replace v-abl in lymphoid transformation-Reference-Cited by-同舟云学术

bcr/abl and src but not myc and ras replace v-abl in lymphoid transformation

Published:1990-08 Issue:8 Volume:10 Page:4365-4369
ISSN:0270-7306
Container-title:Molecular and Cellular Biology
language:en
Short-container-title:Mol Cell Biol

Author:

Engelman A¹,Rosenberg N¹

Affiliation:

1. Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts 02111.

Abstract

Lymphoid cells transformed by temperature-sensitive Abelson virus die at the nonpermissive temperature. This property was exploited to show that bcr/abl and v-src but not myc and ras can replace the transforming signal of v-abl, a result suggesting that the former but not the latter oncogenes transform lymphoid cells via a similar pathway.

Publisher

American Society for Microbiology

Subject

Cell Biology,Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/mcb.10.8.4365-4369.1990

Reference29 articles.

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1. Gag Influences Transformation by Abelson Murine Leukemia Virus and Suppresses Nuclear Localization of the v-Abl Protein;Journal of Virology;2007-09

2. Active Akt and Functional p53 Modulate Apoptosis in Abelson Virus-Transformed Pre-B Cells;Journal of Virology;2004-02-15

3. Absence of p53 Complements Defects in Abelson Murine Leukemia Virus Signaling;Journal of Virology;2003-06

4. The Extreme Carboxyl Terminus of v-Abl Is Required for Lymphoid Cell Transformation by Abelson Virus;Journal of Virology;2003-04-15

5. Temperature-Sensitive Transformation by an Abelson Virus Mutant Encoding an Altered SH2 Domain;Journal of Virology;2001-02-15