Precision Response to the Rise of the SARS-CoV-2 B.1.1.7 Variant of Concern by Combining Novel PCR Assays and Genome Sequencing for Rapid Variant Detection and Surveillance-Reference-Cited by-同舟云学术

Precision Response to the Rise of the SARS-CoV-2 B.1.1.7 Variant of Concern by Combining Novel PCR Assays and Genome Sequencing for Rapid Variant Detection and Surveillance

Published:2021-09-03 Issue:1 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Zelyas Nathan¹²^ORCID,Pabbaraju Kanti³,Croxen Matthew A.¹²⁴,Lynch Tarah³⁵,Buss Emily¹,Murphy Stephanie A.¹⁶,Shokoples Sandy¹,Wong Anita³,Kanji Jamil N.²³⁷,Tipples Graham¹⁴⁸

Affiliation:

1. Alberta Precision Laboratories, Public Health Laboratory, Edmonton, Alberta, Canada

2. Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada

3. Alberta Precision Laboratories, Public Health Laboratory, Calgary, Alberta, Canada

4. Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Alberta, Canada

5. Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada

6. National Microbiology Laboratory, Public Health Agency of Canada, Edmonton, Alberta, Canada

7. Division of Infectious Diseases, Department of Medicine, University of Calgary, Calgary, Alberta, Canada

8. Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada

Abstract

Different strains, or variants, of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, the virus that causes COVID-19) have emerged that have higher levels of transmission, less susceptibility to our immune response, and possibly cause more severe disease than previous strains of the virus. Rapid detection of these variants of concern is important to help contain them and prevent them from spreading widely within the population.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00315-21

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